Marrubium vulgare is widely used in traditional medicine for the treatment of a variety of diseases, including vasorelaxant and antihypertensive activities, anti-inflammatory, antioxidant, analgesic, antispasmodic, hypoglycaemic and hypolipidaemic effects and respiratory disorders. Marrubium vulgare is a popular remedy for cough as well as for digestive disorders. It contains a terpenoid bitter compound marrubiin, diterpenoids, iridoids and flavonoids.